Description

1-Piperidinecarboxylicacid,4-Amino-3,3-Dimethyl-,Ethylester,(-)-(9Ci) is a chiral piperidine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecules with specific stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Catalyst Ligand Precursor: Acts as a starting material for synthesizing chiral ligands used in asymmetric catalysis, enabling more efficient and selective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for research and industrial applications.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, including new route development and stereoselective synthesis.

Basic Information

Product Name	1-Piperidinecarboxylicacid,4-Amino-3,3-Dimethyl-,Ethylester,(-)-(9Ci)
CAS No.	544443-48-3
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	(-)-4-Amino-3,3-dimethylpiperidine-1-carboxylic acid ethyl ester; Ethyl (-)-4-amino-3,3-dimethylpiperidine-1-carboxylate; 4-Amino-3,3-dimethyl-1-piperidinecarboxylic acid ethyl ester, (-)-; 4-Amino-3,3-dimethylpiperidine-1-carboxylic acid ethyl ester; (3S,4S)-4-Amino-3,3-dimethylpiperidine-1-carboxylic acid ethyl ester (stereoisomer); A chiral 4-aminopiperidine ester derivative
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylicacid,4-Amino-3,3-Dimethyl-,Ethylester,(-)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.