Description

1H-Indole-1-Carboxylic Acid, 4-(Acetyloxy)Octahydro-, 1,1-Dimethylethyl Ester, (3As,4R,7As)- is a high-purity, stereochemically defined indole derivative serving as a critical advanced intermediate in complex organic synthesis. This compound matters for its role in constructing intricate molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to build upon the indole scaffold for new product discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides that leverage the indole structure for biological activity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, dyes, and advanced materials requiring specific stereochemistry.
• Academic & Contract Research: Serves as a valuable reagent for methodological studies in organic chemistry and asymmetric synthesis at universities and CROs.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant scale in process optimization.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 4-(Acetyloxy)Octahydro-, 1,1-Dimethylethyl Ester, (3As,4R,7As)-
CAS No.	543910-44-7
Molecular Formula	C17H27NO4
Molecular Weight	309.40 g/mol
Synonyms	tert-Butyl (3aS,4R,7aS)-4-(acetyloxy)octahydro-1H-indole-1-carboxylate; (3aS,4R,7aS)-1-(tert-Butoxycarbonyl)-4-(acetyloxy)octahydro-1H-indole; 4-Acetoxy-1-Boc-octahydroindole (stereoisomer); 1-Boc-4-acetoxy-octahydroindole; Octahydro-1H-indole-1-carboxylic acid, 4-(acetyloxy)-, 1,1-dimethylethyl ester, (3aS,4R,7aS)-; BOC-4-Acetoxy-octahydroindole
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 4-(Acetyloxy)Octahydro-, 1,1-Dimethylethyl Ester, (3As,4R,7As)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.