Description

6-Amino-5-Iodo-Nicotinic Acid is a high-purity, halogenated nicotinic acid derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and iodo functional groups on the pyridine ring, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science: Building block for synthesizing specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and diagnostics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	6-Amino-5-Iodo-Nicotinic Acid
CAS No.	543740-89-2
Molecular Formula	C6H5IN2O2
Molecular Weight	264.02 g/mol
Synonyms	5-Iodo-6-aminonicotinic acid; 6-Amino-5-iodopyridine-3-carboxylic acid; 3-Carboxy-5-iodopyridin-2-amine; 2-Amino-5-iodonicotinic acid; AIA (abbreviation); 543740-89-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 6-Amino-5-Iodo-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.