Description

Cyclohexanecarboxylic Acid, 2-[(4-Pyridinylcarbonyl)Amino]-, (1R,2S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a conformationally constrained cyclohexane ring with a pyridine-based amide linkage, making it an essential precursor for complex molecule construction. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific (1R,2S) configuration can enhance target specificity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-[(4-Pyridinylcarbonyl)Amino]-, (1R,2S)- (9Ci)
CAS No.	541524-09-8
Molecular Formula	C14H16N2O3
Molecular Weight	260.29 g/mol
Synonyms	(1R,2S)-2-[(4-Pyridinecarbonyl)amino]cyclohexanecarboxylic acid; (1R,2S)-2-[(Isonicotinoyl)amino]cyclohexanecarboxylic acid; (1R,2S)-N-(Isonicotinoyl)-2-aminocyclohexanecarboxylic acid; trans-2-(Isonicotinamido)cyclohexanecarboxylic acid (specified enantiomer); (1R,2S)-2-(4-Pyridylcarboxamido)cyclohexanecarboxylic acid; A chiral isonicotinic acid-cyclohexylglycine derivative
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarboxylic Acid, 2-[(4-Pyridinylcarbonyl)Amino]-, (1R,2S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2S)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.