Description

n-(4-Hydroxy-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide is a specialized organic compound featuring a pyridine-hydroxyl scaffold linked to a pivalamide group. This structure makes it a valuable pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or plant growth regulators.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Reagent: Utilized in academic and industrial research for constructing complex heterocyclic compounds.

Basic Information

Product Name	n-(4-Hydroxy-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide
CAS No.	540497-47-0
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	3-(2,2-Dimethylpropanamido)-4-hydroxypyridine; 4-Hydroxy-3-pivalamidopyridine; N-(4-Hydroxy-3-pyridinyl)-2,2-dimethylpropanamide; 2,2-Dimethyl-N-(4-hydroxy-3-pyridinyl)propanamide; Pivalic acid (4-hydroxy-3-pyridinyl)amide; 540497-47-0; 3-Pivalamido-4-hydroxypyridine
EINECS	Contact for details

Quality Control

Our n-(4-Hydroxy-Pyridin-3-Yl)-2,2-Dimethyl-Propionamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.