Description

Piperazine,1-(Trimethylsilyl)-(9Ci) is a specialized organosilicon derivative of piperazine, a key heterocyclic amine. This compound is valued for its role as a versatile silyl-protected intermediate and building block in advanced organic synthesis. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing modified piperazine cores.
• Silylating Agent: Used to introduce the trimethylsilyl (TMS) protecting group onto amines, alcohols, or other functional groups in multi-step synthetic routes.
• Ligand Precursor: Serves as a starting material for the development of novel ligands used in catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate in the development of new crop protection agents and pesticides.
• Material Science: Used in the research and production of specialty polymers and silicon-containing hybrid materials.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in both university and corporate research laboratories.

Basic Information

Product Name	Piperazine,1-(Trimethylsilyl)-(9Ci)
CAS No.	540494-46-0
Molecular Formula	C7H18N2Si
Molecular Weight	158.32 g/mol
Synonyms	1-(Trimethylsilyl)piperazine; N-(Trimethylsilyl)piperazine; Piperazine, 1-(trimethylsilyl)-; 1-Trimethylsilylpiperazine; N-Trimethylsilylpiperazine; TMS-Piperazine; (Trimethylsilyl)piperazine
EINECS	Contact for details

Quality Control

Our Piperazine,1-(Trimethylsilyl)-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.