Description

Benzamide, 2-Amino-n-(2,6-Dioxo-3-Piperidinyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted small-molecule drugs, particularly in oncology and immunology research.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of novel heterobifunctional degraders.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of tool compounds for studying specific biological pathways and protein functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and biochemical studies.

Basic Information

Product Name	Benzamide, 2-Amino-n-(2,6-Dioxo-3-Piperidinyl)- (9Ci)
CAS No.	537696-00-7
Molecular Formula	C12H13N3O3
Molecular Weight	247.25 g/mol
Synonyms	2-Amino-N-(2,6-dioxopiperidin-3-yl)benzamide; 3-(2-Aminobenzamido)piperidine-2,6-dione; Thalidomide metabolite derivative; Aminobenzamide-piperidinedione conjugate; Lenalidomide/Pomalidomide related intermediate; Immunomodulatory imide drug (IMiD) precursor; EINECS Contact for details

Quality Control

Our production of Benzamide, 2-Amino-n-(2,6-Dioxo-3-Piperidinyl)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.