Description

1-[2-[(2R)-4-[2-[3,5-Bis(Trifluoromethyl)Phenyl]Acetyl]-2-(3,4-Dichlorophenyl)-2-Morpholinyl]Ethyl]-Alpha,α-Dimethyl-4-Piperidineacetamide is a high-purity, complex organic intermediate of significant interest in advanced pharmaceutical research and development. This compound matters as a critical building block for synthesizing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments. Pharmaceutical companies, contract research organizations (CROs), and academic research institutions require this material for drug discovery programs, process chemistry development, and analytical method validation.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new chemical entities (NCEs) for clinical trials.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a standard or reference material for scaling up synthetic routes from lab to pilot plant.
• Analytical Standard: Employed as a high-purity reference standard for HPLC, LC-MS, and NMR method development and validation.
• Biochemical Research: Potential use as a tool compound for investigating specific biological pathways and target engagement.
• Custom Synthesis: Basis for the preparation of more complex, labeled (e.g., deuterated, C13) or conjugated derivatives for specialized research applications.

Basic Information

Item	Detail
Product Name	1-[2-[(2R)-4-[2-[3,5-Bis(Trifluoromethyl)Phenyl]Acetyl]-2-(3,4-Dichlorophenyl)-2-Morpholinyl]Ethyl]-Alpha,α-Dimethyl-4-Piperidineacetamide
CAS No.	537034-22-3
Molecular Formula	C31H29Cl2F6N3O3
Molecular Weight	684.48 g/mol
Synonyms	BMS-214662; BMS214662; (R)-1-[2-[4-[2-[3,5-Bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)morpholin-2-yl]ethyl]-α,α-dimethyl-4-piperidineacetamide; 1-[2-[(2R)-4-[2-[3,5-Bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]-α,α-dimethyl-4-piperidineacetamide; 4-Piperidineacetamide, 1-[2-[(2R)-4-[2-[3,5-bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]-α,α-dimethyl-
EINECS	Contact for details

Quality Control

Our 1-[2-[(2R)-4-[2-[3,5-Bis(Trifluoromethyl)Phenyl]Acetyl]-2-(3,4-Dichlorophenyl)-2-Morpholinyl]Ethyl]-Alpha,α-Dimethyl-4-Piperidineacetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and LC-MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.