Description

1-(4-Amino-3-Fluorophenyl)Pyridin-2(1H)-One is a high-purity fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which combines a fluorinated aniline moiety with a lactam ring, enabling precise modifications in complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning the properties of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Acts as a precursor for specialty polymers and liquid crystals, contributing to the development of advanced functional materials.
• Chemical Biology Probes: Employed in the design of molecular probes and fluorescent tags for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	1-(4-Amino-3-Fluorophenyl)Pyridin-2(1H)-One
CAS No.	536747-52-1
Molecular Formula	C11H9FN2O
Molecular Weight	204.20 g/mol
Synonyms	1-(4-Amino-3-fluorophenyl)-2(1H)-pyridinone; 1-(4-Amino-3-fluorophenyl)pyridin-2-one; 2(1H)-Pyridinone, 1-(4-amino-3-fluorophenyl)-; 4-Amino-3-fluoro-1-(2-oxo-1,2-dihydropyridin-1-yl)benzene; 1-(4-Amino-3-fluorophenyl)-1,2-dihydropyridin-2-one; 1-(4-Amino-3-fluorophenyl)-2-pyridone; 3-Fluoro-4-(2-oxopyridin-1(2H)-yl)aniline
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-3-Fluorophenyl)Pyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.