Description

6-Dimethylamino-4-Methyl-Pyridineboronic Acid is a specialized organoboron compound that serves as a versatile building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a dimethylamino-substituted pyridine scaffold that can act as a ligand or directing group. This chemical is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing heterocyclic systems.
• Suzuki-Miyaura Cross-Coupling: Used as a boronic acid coupling partner for the formation of carbon-carbon bonds between aromatic and heteroaromatic rings.
• Ligand Synthesis: The pyridine nitrogen and dimethylamino group make it a useful starting material for creating novel catalysts and chelating ligands in transition metal catalysis.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides that require specific heterocyclic motifs.
• Material Science: Potential monomer or functionalizing agent for creating advanced organic electronic materials or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules or inhibitors for studying biological pathways and protein function.

Basic Information

Product Name	6-Dimethylamino-4-Methyl-Pyridineboronic Acid
CAS No.	535934-70-4
Molecular Formula	C8H13BN2O2
Molecular Weight	180.01 g/mol
Synonyms	(6-(Dimethylamino)-4-methylpyridin-3-yl)boronic acid; 3-Borono-6-(dimethylamino)-4-methylpyridine; 6-Dimethylamino-4-methylpyridine-3-boronic acid; 5-Borono-2-(dimethylamino)-4-picoline; 4-Methyl-6-(dimethylamino)pyridine-3-boronic acid; 6-(N,N-Dimethylamino)-4-methyl-3-pyridineboronic acid
EINECS	Contact for details

Quality Control

Our 6-Dimethylamino-4-Methyl-Pyridineboronic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.