Description

Erteberel (LY500307) is a potent and selective nonsteroidal estrogen receptor alpha (ERα) agonist, identified by the CAS registry number 533884-09-2. This compound is a critical research tool for investigating ERα-mediated signaling pathways and their roles in physiology and disease. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, oncology, and metabolic disorders.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and development of novel estrogen receptor-targeted therapies.
• Biochemical Assays: Used as a selective agonist in cell-based and in vitro assays to study ERα receptor function, gene regulation, and cellular responses.
• Academic & Preclinical Studies: Facilitates fundamental research into the role of ERα in various biological systems, including bone metabolism, cardiovascular function, and central nervous system activity.
• Oncology Research: Employed in studies exploring the differential effects of ERα activation in hormone-sensitive cancers and other proliferative diseases.
• Metabolic Disorder Investigations: Aids in research focused on the influence of estrogen signaling on glucose homeostasis, lipid metabolism, and energy balance.
• High-Throughput Screening (HTS): Acts as a control compound in screening campaigns designed to identify new ERα modulators or inhibitors.

Basic Information

Product Name	Erteberel (LY500307)
CAS No.	533884-09-2
Molecular Formula	C19H18N2O3S
Molecular Weight	354.42 g/mol
Synonyms	LY-500307; LY500307; 3-(4-Fluorophenyl)-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]-4-methyl-2H-1-benzothiopyran-2-one; Erteberel; Nonsteroidal ERα agonist LY500307; Selective Estrogen Receptor Alpha Agonist LY500307
EINECS	Contact for details

Quality Control

Our Erteberel (LY500307) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.