Description

Methyl 2-Amino-2-(3-Chlorophenyl)Acetate is a versatile chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in the presence of both an amino ester functional group and a chlorinated aromatic ring, which allows for diverse downstream modifications. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators with specific activity.
• Peptidomimetics Research: Used to incorporate non-natural amino acid residues into peptide analogs for medicinal chemistry studies.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.

Basic Information

Product Name	Methyl 2-Amino-2-(3-Chlorophenyl)Acetate
CAS No.	532987-11-4
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	Methyl 2-Amino-(3-chlorophenyl)acetate; (3-Chlorophenyl)glycine methyl ester; 2-Amino-2-(3-chlorophenyl)acetic acid methyl ester; Methyl α-amino-3-chlorobenzeneacetate; DL-3-Chlorophenylglycine methyl ester; Methyl (3-chlorophenyl)glycinate; α-Amino-3-chlorobenzeneacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-2-(3-Chlorophenyl)Acetate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.