Description

2-Methoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex molecular architectures, which is critical for developing new active compounds. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel drug candidates, crop protection agents, and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and CNS drug discovery.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in academic laboratories and CROs (Contract Research Organizations).
• Custom Synthesis: Provides a versatile handle for the custom synthesis of complex, boronic ester-functionalized pyridine derivatives for specialized client projects.

Basic Information

Product Name	2-Methoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine
CAS No.	532391-31-4
Molecular Formula	C12H18BNO3
Molecular Weight	235.09 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxypyridine; 2-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methoxypyridine-3-boronic acid pinacol ester; Pyridine, 2-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Pyridineboronic acid, 2-methoxy-, 1,1-dimethylethyl ester; 2-Methoxy-3-pyridinylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methoxy-3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.