Description

5-Bromo-2,4,6-Trimethylnicotinonitrile is a high-purity, multi-functional chemical intermediate featuring a brominated pyridine core. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value nitrile-functionalized heterocycles.

Basic Information

Product Name	5-Bromo-2,4,6-Trimethylnicotinonitrile
CAS No.	531521-32-1
Molecular Formula	C9H9BrN2
Molecular Weight	225.09 g/mol
Synonyms	5-Bromo-2,4,6-trimethyl-3-pyridinecarbonitrile; 3-Cyano-5-bromo-2,4,6-trimethylpyridine; 5-Bromo-2,4,6-trimethylnicotinonitrile; 2,4,6-Trimethyl-5-bromonicotinonitrile; Nicotinonitrile, 5-bromo-2,4,6-trimethyl-; 5-Bromo-2,4,6-trimethyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2,4,6-Trimethylnicotinonitrile is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.