Description

(As,R)-A,-Dihydroxy-2-Pyridinepropanoic Acid Ethyl Ester, 1-Oxide is a specialized chiral pyridine derivative with significant utility in advanced chemical synthesis. This compound serves as a critical building block and intermediate for the development of complex molecules, particularly in pharmaceutical research. It is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity, structurally defined intermediates for process development and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced crop protection agents and herbicides, leveraging its unique pyridine-based structure.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals, flavors, and fragrances.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, including studies on oxidation and esterification reactions.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in regulated industries.

Basic Information

Product Name	(As,R)-A,-Dihydroxy-2-Pyridinepropanoic Acid Ethyl Ester, 1-Oxide
CAS No.	529474-73-5
Molecular Formula	C10H13NO5
Molecular Weight	227.21 g/mol
Synonyms	Ethyl (2R)-2,3-dihydroxy-2-(pyridin-1-ium-1-yl)propanoate 1-oxide; (R)-2,3-Dihydroxy-2-(1-oxidopyridin-1-ium-1-yl)propanoic acid ethyl ester; 2-Pyridinepropanoic acid, α,β-dihydroxy-, ethyl ester, 1-oxide, (αR)-; Ethyl (R)-α,β-dihydroxy-2-pyridinepropanoate 1-oxide; (R)-Ethyl 2,3-dihydroxy-2-(pyridin-1-ium-1-yl)propanoate oxide
EINECS	Contact for details

Quality Control

Our (As,R)-A,-Dihydroxy-2-Pyridinepropanoic Acid Ethyl Ester, 1-Oxide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring it meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.