Description

4'-(Aminomethyl)-Biphenyl-4-Carboxylic Acid tert-Butyl Ester is a high-purity, bifunctional organic building block featuring both a protected carboxylic acid and a primary amine group. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for constructing complex target molecules. It is primarily utilized in the pharmaceutical and advanced materials sectors for applications such as medicinal chemistry and polymer synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Peptidomimetic Synthesis: Serves as a versatile scaffold for constructing peptide analogs and mimetics due to its amine and protected carboxylate functionalities.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with tailored properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Utilized as an intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	4'-(Aminomethyl)-Biphenyl-4-Carboxylic Acid tert-Butyl Ester
CAS No.	528894-33-9
Molecular Formula	C19H23NO2
Molecular Weight	297.39 g/mol
Synonyms	4'-(Aminomethyl)-[1,1'-biphenyl]-4-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4'-(aminomethyl)biphenyl-4-carboxylate; 4'-(Aminomethyl)biphenyl-4-carboxylic acid tert-butyl ester; Biphenyl-4-carboxylic acid, 4'-(aminomethyl)-, 1,1-dimethylethyl ester; [1,1'-Biphenyl]-4-carboxylic acid, 4'-(aminomethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4'-(Aminomethyl)-Biphenyl-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.