Description

2(1H)-Azetone, 1-Ethynyl-4-Isocyanato- (9Ci) is a specialized heterocyclic building block containing both an isocyanate and an ethynyl functional group, enabling versatile reactivity for advanced synthesis. This compound is critical for the development of novel polymers, pharmaceutical intermediates, and high-performance materials requiring precise molecular architecture. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Polymer Science: Used as a monomer or cross-linking agent in the production of specialty polyurethanes, polyureas, and other high-performance polymers.
• Agrochemical Research: Employed in the development of new generation herbicides, fungicides, and plant growth regulators.
• Material Science: Facilitates the creation of advanced coatings, adhesives, and composites with enhanced thermal or mechanical properties.
• Chemical Synthesis: Acts as a versatile building block for heterocyclic chemistry, enabling the construction of complex azetidine and related ring systems.
• Life Sciences & Bioconjugation: Potential use in probe and linker chemistry for bioconjugation applications due to its reactive handles.

Basic Information

Product Name	2(1H)-Azetone, 1-Ethynyl-4-Isocyanato- (9Ci)
CAS No.	528871-30-9
Molecular Formula	C6H4N2O
Molecular Weight	120.11 g/mol
Synonyms	1-Ethynyl-4-isocyanato-2(1H)-azetone; 4-Isocyanato-1-ethynyl-1,2-dihydro-2-azetinone; 1-Ethynyl-4-isocyanatoazetidin-2-one; Azetidin-2-one, 1-ethynyl-4-isocyanato-; 1-Ethynyl-4-isocyanato-2-azetidinone; 528871-30-9; 4-Isocyanato-1-ethynylazetidin-2-one
EINECS	Contact for details

Quality Control

Our 2(1H)-Azetone, 1-Ethynyl-4-Isocyanato- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems support compliance with cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.