Description

1,4-Dioxa-7-Azaspiro[4.5]Decane-7-Carboxylic Acid, Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile building block for medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring spirocyclic or complex heterocyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry and functional groups are required.
• Organic Synthesis Reagent: Serves as a protected amino acid derivative or a versatile scaffold for constructing complex molecules in academic and industrial research.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional organic materials.

Basic Information

Product Name	1,4-Dioxa-7-Azaspiro[4.5]Decane-7-Carboxylic Acid, Phenylmethyl Ester
CAS No.	528594-63-0
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	Benzyl 1,4-dioxa-7-azaspiro[4.5]decane-7-carboxylate; 7-(Benzyloxycarbonyl)-1,4-dioxa-7-azaspiro[4.5]decane; 7-Cbz-1,4-dioxa-7-azaspiro[4.5]decane; 1,4-Dioxa-7-azaspiro[4.5]decane-7-carboxylic acid benzyl ester; N-Cbz-4-piperidone ethylene ketal; 4-Piperidone ethylene ketal, N-carbobenzoxy-; N-Carbobenzyloxy-4-piperidone ethylene ketal; Benzyl 7-aza-1,4-dioxaspiro[4.5]decane-7-carboxylate
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-7-Azaspiro[4.5]Decane-7-Carboxylic Acid, Phenylmethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.