Description

2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid is a high-value heterocyclic carboxylic acid building block, recognized for its fused dioxino-pyridine scaffold. This compound is essential for advanced pharmaceutical research and development, serving as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce novel molecular architectures into their target compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique fused-ring system that can modulate bioavailability and receptor binding.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides or fungicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: The carboxylic acid functionality and heterocyclic nitrogen make it suitable for designing novel chelating ligands and organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and advanced materials requiring specific heterocyclic motifs.

Basic Information

Product Name	2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic Acid
CAS No.	527681-13-6
Molecular Formula	C9H7NO4
Molecular Weight	193.16 g/mol
Synonyms	7-Carboxy-2,3-dihydro-1,4-dioxino[2,3-c]pyridine; 1,4-Dioxino[2,3-c]pyridine-7-carboxylic acid, 2,3-dihydro-; 2,3-Dihydro-1,4-dioxino[2,3-c]pyridine-7-carboxylic acid; Dioxinopyridinecarboxylic acid; CAS 527681-13-6
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its carboxylic acid nature, keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay	95.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.