Description

Hexahydro-2-[(2-Methyl-4-Pyridinyl)Methyl]-1H-Azepine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially for neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the complex multi-step synthesis of target molecules during process research and scale-up.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial API batches under cGMP conditions.
• Biochemical Research: Utilized as a reference standard or a reagent in biochemical assays and pharmacological studies.

Basic Information

Product Name	Hexahydro-2-[(2-Methyl-4-Pyridinyl)Methyl]-1H-Azepine
CAS No.	527674-27-7
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	2-[(2-Methylpyridin-4-yl)methyl]hexahydro-1H-azepine; 1H-Azepine, hexahydro-2-[(2-methyl-4-pyridinyl)methyl]-; 2-((2-Methylpyridin-4-yl)methyl)hexahydro-1H-azepine; 4-((Hexahydro-1H-azepin-2-yl)methyl)-2-methylpyridine; 2-(2-Methyl-4-pyridylmethyl)hexamethyleneimine; Hexamethyleneimine, 2-[(2-methyl-4-pyridinyl)methyl]-
EINECS	Contact for details

Quality Control

Our Hexahydro-2-[(2-Methyl-4-Pyridinyl)Methyl]-1H-Azepine is manufactured under strict quality management systems. We offer material suitable for research and GMP-grade applications, with purity typically exceeding 98.0% (by HPLC). Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality commitment ensures reliable supply and batch-to-batch consistency for your critical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.