Description

2-((1-Isopropyl-2,5-Dioxopyrrolidin-3-Yl)Thio)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of proprietary drug candidates, especially those with heterocyclic core structures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• API Development: Employed in the scalable production of active pharmaceutical ingredients requiring the nicotinic acid-pyrrolidinedione hybrid framework.
• Bioconjugation & Probe Synthesis: Potential utility in creating chemical probes or conjugates for biochemical and diagnostic applications due to its functional groups.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis projects for client-specific molecules.

Basic Information

Product Name	2-((1-Isopropyl-2,5-Dioxopyrrolidin-3-Yl)Thio)Nicotinic Acid
CAS No.	526190-73-8
Molecular Formula	C13H14N2O4S
Molecular Weight	294.33 g/mol
Synonyms	2-[(1-Isopropyl-2,5-dioxo-3-pyrrolidinyl)thio]-3-pyridinecarboxylic acid; Nicotinic acid, 2-[(1-isopropyl-2,5-dioxo-3-pyrrolidinyl)thio]-; 2-((1-Isopropyl-2,5-dioxopyrrolidin-3-yl)thio)pyridine-3-carboxylic acid; 2-(1-Isopropyl-2,5-dioxo-3-pyrrolidinylthio)nicotinic acid; 526190-73-8; 2-[(1-Isopropyl-2,5-dioxopyrrolidin-3-yl)sulfanyl]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-((1-Isopropyl-2,5-Dioxopyrrolidin-3-Yl)Thio)Nicotinic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.