Description

2-{[4-Cyclohexyl-5-(Pyridin-3-Yl)-4H-1,2,4-Triazol-3-Yl]Sulfanyl}-n-(4-Fluorophenyl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates with potential antitumor or neuroactive properties.
• Medicinal Chemistry Research: Serves as a core scaffold in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• API Development: Used in the pilot-scale and commercial-scale production of active pharmaceutical ingredients for clinical trials and manufacturing.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	2-{[4-Cyclohexyl-5-(Pyridin-3-Yl)-4H-1,2,4-Triazol-3-Yl]Sulfanyl}-n-(4-Fluorophenyl)Acetamide
CAS No.	525582-88-1
Molecular Formula	C21H22FN5OS
Molecular Weight	411.50 g/mol
Synonyms	2-({4-Cyclohexyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(4-fluorophenyl)acetamide; N-(4-Fluorophenyl)-2-{[4-cyclohexyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide; 2-((4-Cyclohexyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-fluorophenyl)acetamide; Acetamide, 2-[[4-cyclohexyl-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-N-(4-fluorophenyl)-; CAS 525582-88-1
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles. We support compliance with ICH guidelines and can tailor specifications to meet specific customer requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.