Description

3-Chloro-4-(Pyridin-2-Ylmethoxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aniline and pyridine-based structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific substitution pattern enables targeted molecular modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Acts as a specialized intermediate for manufacturing complex dyes, pigments, and other performance chemicals.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	3-Chloro-4-(Pyridin-2-Ylmethoxy)Aniline
CAS No.	524955-09-7
Molecular Formula	C₁₂H₁₁ClN₂O
Molecular Weight	234.68 g/mol
Synonyms	3-Chloro-4-[(pyridin-2-yl)methoxy]aniline; 3-Chloro-4-(2-pyridylmethoxy)aniline; 4-Amino-2-chloro-1-(2-pyridylmethoxy)benzene; 2-[(4-Amino-2-chlorophenoxy)methyl]pyridine; 524955-09-7; Benzenamine, 3-chloro-4-[(2-pyridinyl)methoxy]-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Pyridin-2-Ylmethoxy)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We adhere to cGMP standards where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.