Description

3-Chloro-4-(3-Fluorophenoxy)Aniline is a high-purity, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and high-performance agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated phenoxy aniline motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the manufacture of herbicides and pesticides, where the chloro and fluorophenoxy groups contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced functional materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its rigid, halogenated aromatic structure.
• Dye & Pigment Intermediate: Employed in the production of specialized azo dyes and high-performance pigments that require specific lightfastness and color properties.
• Polymer Modification: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, such as polyimides or epoxy resins, to enhance thermal and chemical resistance.
• Chemical Research & Development: Utilized in academic and industrial labs for methodological studies in cross-coupling reactions, amination, and other catalytic transformations.

Basic Information

Product Name	3-Chloro-4-(3-Fluorophenoxy)Aniline
CAS No.	524953-60-4
Molecular Formula	C12H9ClFNO
Molecular Weight	237.66 g/mol
Synonyms	4-Amino-2-chloro-1-(3-fluorophenoxy)benzene; 2-Chloro-4-amino-1-(3-fluorophenoxy)benzene; 3-Chloro-4-(3-fluorophenoxy)benzenamine; 1-Chloro-2-(3-fluorophenoxy)-4-aminobenzene; Benzenamine, 3-chloro-4-(3-fluorophenoxy)-; 3-Fluoro-4'-chloro-4-aminodiphenyl ether
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(3-Fluorophenoxy)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent oxidation and moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.