Description

Spiro[Cyclopropane-1,3(1H)-Isoxazolo[4,3-C]Pyridine] (9Ci) is a complex spirocyclic organic compound featuring a fused isoxazolopyridine core, serving as a valuable and sophisticated chemical building block. This compound matters for its role in advanced pharmaceutical research and development, particularly in the synthesis of novel drug candidates targeting complex biological pathways. It is primarily needed by medicinal chemists and R&D departments in the pharmaceutical and biotechnology industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or anti-infective targets.
• Medicinal Chemistry Research: Used as a core scaffold or a privileged structure for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to introduce the unique spiro[cyclopropane-isoxazolopyridine] moiety into target molecules.
• Agrochemical Research: Potential application as an intermediate in the synthesis of novel crop protection agents and pesticides.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in heterocyclic and synthetic organic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and chemical industry clients with custom synthesis projects.

Basic Information

Item	Detail
Product Name	Spiro[Cyclopropane-1,3(1H)-Isoxazolo[4,3-C]Pyridine] (9Ci)
CAS No.	524950-38-7
Molecular Formula	C9H8N2O
Molecular Weight	160.17 g/mol
Synonyms	Spiro[cyclopropane-1,3'-isoxazolo[4,3-c]pyridine]; 1'H-Spiro[cyclopropane-1,3'-isoxazolo[4,3-c]pyridine]; 1'H-Spiro(cyclopropane-1,3'-isoxazolo[4,3-c]pyridine); Spiro(cyclopropane-1,3(1H)-isoxazolo[4,3-c]pyridine); 524950-38-7; Spiro[cyclopropane-1,3(1H)-isoxazolo[4,3-c]pyridine]; Spiro[cyclopropane-1,3(1'H)-isoxazolo[4,3-c]pyridine]
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopropane-1,3(1H)-Isoxazolo[4,3-C]Pyridine] (9Ci) is produced under strict quality management protocols. All batches undergo rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, purity by HPLC, and residual solvent levels. Our quality systems are designed to support cGMP and ISO-aligned manufacturing for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.