Description

2-(4-Cbz-Piperazin-1-Yl)Pyridine-5-Boronic Acid is a sophisticated boronic acid derivative and a key building block in modern synthetic chemistry. Its primary value lies in its dual functionality, serving as a crucial intermediate in the synthesis of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct novel active pharmaceutical ingredients (APIs) and advanced chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl/heteroaryl halides and boronic acids, a cornerstone reaction in medicinal chemistry and material science.
• Chemical Biology & Proteomics: Used in the development of chemical probes and affinity ligands for studying biological pathways and protein function.
• Agrochemical Research: Serves as a building block for creating novel pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and conductive polymers.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery programs.

Basic Information

Product Name	2-(4-Cbz-Piperazin-1-Yl)Pyridine-5-Boronic Acid
CAS No.	521985-18-2
Molecular Formula	C23H24BN3O4
Molecular Weight	417.27 g/mol
Synonyms	2-[4-[(Benzyloxy)carbonyl]-1-piperazinyl]-5-pyridineboronic Acid; 5-Borono-2-[4-(phenylmethoxycarbonyl)-1-piperazinyl]pyridine; 2-(4-Carbobenzyloxy-piperazin-1-yl)pyridine-5-boronic Acid; 2-(4-Cbz-1-piperazinyl)-5-pyridineboronic Acid; 2-(N-Cbz-piperazin-1-yl)pyridine-5-boronic Acid; 2-(4-(Benzyloxycarbonyl)piperazin-1-yl)pyridine-5-boronic Acid; 521985-18-2; 2-(4-CBZ-PIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID
EINECS	Contact for details

Quality Control

Our 2-(4-Cbz-Piperazin-1-Yl)Pyridine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.