Description

2,4-Dideoxy-3,5-o-(1-Methylethylidene)-6-o-(Phenylmethyl)-L-Threo-Hexonic Acid tert-Butyl Ester is a sophisticated chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its protected sugar acid structure, which serves as a key building block for the construction of complex bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of antiviral agents, enzyme inhibitors, and carbohydrate-based drugs. The CAS number for this compound is 521974-02-7.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of nucleoside analogs and other antiviral or anticancer drug candidates.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Enzyme Inhibitor Development: Serves as a precursor for designing transition-state analogs that target specific glycosidases or other carbohydrate-processing enzymes.
• Chemical Biology Probes: Employed in the creation of labeled or modified sugars to investigate biological pathways and mechanisms.
• Process Chemistry: Utilized in scale-up and optimization studies for the production of active pharmaceutical ingredients (APIs) requiring this specific stereochemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2,4-Dideoxy-3,5-o-(1-Methylethylidene)-6-o-(Phenylmethyl)-L-Threo-Hexonic Acid tert-Butyl Ester
CAS No.	521974-02-7
Molecular Formula	C20H28O6
Molecular Weight	364.44 g/mol
Synonyms	tert-Butyl 2,4-dideoxy-3,5-O-(1-methylethylidene)-6-O-benzyl-L-threo-hexonate; 6-O-Benzyl-2,4-dideoxy-3,5-O-isopropylidene-L-threo-hexonic acid tert-butyl ester; L-threo-Hexonic acid, 2,4-dideoxy-3,5-O-(1-methylethylidene)-6-O-(phenylmethyl)-, 1,1-dimethylethyl ester; Benzyl-protected isopropylidene L-threonate tert-butyl ester; Advanced sugar acid derivative intermediate
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dideoxy-3,5-o-(1-Methylethylidene)-6-o-(Phenylmethyl)-L-Threo-Hexonic Acid tert-Butyl Ester is produced and controlled under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.