Description

Methyl 4-Chloro-9H-Pyrimido[4,5-B]Indole-6-Carboxylate is a high-purity, heterocyclic organic compound with the CAS number 521286-75-9, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its complex fused-ring structure makes it a valuable scaffold for synthesizing novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for building next-generation molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Material Science Precursor: Serves as a precursor for organic electronic materials and specialty dyes due to its conjugated indole-pyrimidine system.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.
• Academic & Institutional Research: Used in university and institutional labs for fundamental studies in heterocyclic chemistry and new reaction methodologies.

Basic Information

Product Name	Methyl 4-Chloro-9H-Pyrimido[4,5-B]Indole-6-Carboxylate
CAS No.	521286-75-9
Molecular Formula	C13H8ClN3O2
Molecular Weight	273.67 g/mol
Synonyms	4-Chloro-9H-pyrimido[4,5-b]indole-6-carboxylic acid methyl ester; Methyl 4-chloro-9H-pyrimido[4,5-b]indole-6-carboxylate; 9H-Pyrimido[4,5-b]indole-6-carboxylic acid, 4-chloro-, methyl ester; 521286-75-9; 4-Chloro-9H-pyrimido[4,5-b]indole-6-methyl carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all critical parameters are available upon request, providing full traceability and supporting your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.