Description

1,3-Di-o-Benzyl-2-o-Lauroylglycerol is a synthetic glycerol derivative where the 1 and 3 hydroxyl groups are protected by benzyl ethers and the 2 position is esterified with lauric acid. This specific molecular architecture makes it a valuable protected intermediate and building block in organic synthesis, particularly for the controlled construction of complex lipids and phospholipids. It is essential for researchers and manufacturers in the pharmaceutical and specialty chemical sectors developing novel drug delivery systems, prodrugs, and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of phospholipids, lysophospholipids, and other membrane-targeting agents used in drug formulation.
• Lipid Research: Serves as a protected precursor in the study of lipid metabolism, enzyme substrates, and the development of lipid-based drug carriers (e.g., liposomes, solid lipid nanoparticles).
• Prodrug Synthesis: Utilized in creating prodrugs where active pharmaceutical ingredients (APIs) are conjugated via the glycerol backbone for improved bioavailability or targeted release.
• Chemical Synthesis: Acts as a versatile intermediate in organic chemistry for introducing specific fatty acid chains (lauric acid) into more complex molecular frameworks under controlled conditions.
• Bioconjugation: Used in the development of chemical linkers and spacers for attaching molecules to surfaces or other biomolecules in diagnostic and therapeutic applications.

Basic Information

Item	Details
Product Name	1,3-Di-o-Benzyl-2-o-Lauroylglycerol
CAS No.	519177-07-2
Molecular Formula	C35H44O5
Molecular Weight	544.73 g/mol
Synonyms	1,3-Di-O-benzyl-2-O-lauroylglycerol; 1,3-Dibenzyl-2-lauroylglycerol; 2-Lauroyl-1,3-dibenzylglycerol; 1,3-Dibenzyl-2-lauroyl-sn-glycerol; sn-Glycerol 1,3-dibenzy ether 2-laurate; Lauric acid 1,3-dibenzyl glycerol ester; Glycerol 1,3-dibenzyl ether 2-laurate
EINECS	Contact for details

Quality Control

Our 1,3-Di-o-Benzyl-2-o-Lauroylglycerol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles is provided with every shipment to support your research and development or cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 97.0%
Melting Point	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.