Description

1,4,6,7-Tetrahydro-Pyrazolo[4,3-C]Pyridine-3,5-Dicarboxylic Acid 5-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant synthetic utility. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery and synthesis optimization programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex heterocyclic drug candidates, especially for neurological and psychiatric targets.
• Drug Discovery Research: Used as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in the scale-up and route scouting for new chemical entities (NCEs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.
• Academic Research: Utilized in university and institutional labs for the study of novel organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	1,4,6,7-Tetrahydro-Pyrazolo[4,3-C]Pyridine-3,5-Dicarboxylic Acid 5-tert-Butyl Ester
CAS No.	518990-56-2
Molecular Formula	C13H17N3O4
Molecular Weight	279.29 g/mol
Synonyms	5-tert-Butyl 1,4,6,7-tetrahydro-3H-pyrazolo[4,3-c]pyridine-3,5-dicarboxylate; 5-O-tert-Butyl 1,4,6,7-tetrahydro-3H-pyrazolo[4,3-c]pyridine-3,5-dicarboxylate; 1,4,6,7-Tetrahydro-3H-pyrazolo[4,3-c]pyridine-3,5-dicarboxylic acid 5-(1,1-dimethylethyl) ester; Pyrazolopyridine-3,5-dicarboxylic acid 5-tert-butyl ester derivative; tert-Butyl 1,4,6,7-tetrahydro-3H-pyrazolo[4,3-c]pyridine-5-carboxylate-3-carboxylate (tautomeric form).
EINECS	Contact for details

Quality Control

Our 1,4,6,7-Tetrahydro-Pyrazolo[4,3-C]Pyridine-3,5-Dicarboxylic Acid 5-tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.