Description

6-Chloro-2-Iodo-3-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists developing specialty chemicals and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis, enabling new synthetic methodologies.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers, organic light-emitting diodes (OLEDs), and liquid crystals.
• Chemical Biology Probe: Utilized as a building block for synthesizing molecular probes and tags due to the reactivity of the iodine atom for further functionalization (e.g., cross-coupling, radioiodination).
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	6-Chloro-2-Iodo-3-(Trifluoromethyl)Pyridine
CAS No.	518057-64-2
Molecular Formula	C6H2ClF3IN
Molecular Weight	321.44 g/mol
Synonyms	2-Iodo-6-chloro-3-(trifluoromethyl)pyridine; 3-Trifluoromethyl-6-chloro-2-iodopyridine; 6-Chloro-2-iodo-3-trifluoromethylpyridine; 2-Iodo-6-chloro-α,α,α-trifluoro-3-picoline; Pyridine, 6-chloro-2-iodo-3-(trifluoromethyl)-; 6-Chloro-2-iodo-3-(trifluoromethyl)pyridine; 6-Chloro-2-iodo-3-(trifluoromethyl)pyridine, 95+%
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Iodo-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.