Description

Carbamic Acid, [(2R)-2-Methyl-3-Oxopropyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters as a key protected intermediate for constructing complex molecules with defined stereochemistry, ensuring precise control over the final product's biological and chemical properties. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where the specific stereoisomer can significantly impact efficacy and environmental safety.
• Peptide Mimetics & Prodrug Synthesis: Serves as a protected precursor for introducing specific amino acid-like or carbonyl-containing functionalities into larger molecular architectures.
• Asymmetric Catalysis Ligand Precursor: Provides a chiral scaffold for the development of novel ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for stereoselective reactions in academic and industrial R&D laboratories.

Basic Information

Product Name	Carbamic Acid, [(2R)-2-Methyl-3-Oxopropyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	518038-34-1
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	(R)-tert-Butyl (2-methyl-3-oxopropyl)carbamate; (R)-3-((tert-Butoxycarbonyl)amino)-2-methylpropanal; (2R)-2-Methyl-3-oxopropylcarbamic acid tert-butyl ester; tert-Butyl N-[(2R)-2-methyl-3-oxopropyl]carbamate; Boc-D-alaninal; (R)-Boc-β-alaninal (methyl substituted); (R)-N-Boc-3-amino-2-methylpropanal
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(2R)-2-Methyl-3-Oxopropyl]-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent in-process controls to ensure batch-to-batch consistency and high chiral purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral HPLC, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in cGMP and ISO 9001 environments for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store the product at 2-8°C under an inert atmosphere. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.