Description

2-(2-Methylpropyl)-1,3-Dioxo-n-(Pyridin-3-Ylmethyl)-2,3-Dihydro-1H-Isoindole-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates and investigational new drugs.
• Organic Synthesis Building Block: Used in research laboratories for constructing complex isoindole-1,3-dione and carboxamide-containing molecules.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for advanced applications.
• Bioconjugation & Probe Development: Potential use in developing labeled compounds or probes for biochemical and diagnostic research due to its functional groups.

Basic Information

Product Name	2-(2-Methylpropyl)-1,3-Dioxo-n-(Pyridin-3-Ylmethyl)-2,3-Dihydro-1H-Isoindole-5-Carboxamide
CAS No.	518022-01-0
Molecular Formula	C19H19N3O3
Molecular Weight	337.37 g/mol
Synonyms	5-Carboxamido-2-isobutyl-1H-isoindole-1,3(2H)-dione N-(3-Pyridinylmethyl) derivative; N-(Pyridin-3-ylmethyl)-2-(2-methylpropyl)-1,3-dioxoisoindoline-5-carboxamide; 2-Isobutyl-N-(pyridin-3-ylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxamide; 5-Carboxamido-2-isobutylphthalimide N-(3-picolyl) derivative; 1H-Isoindole-5-carboxamide, 2,3-dihydro-2-(2-methylpropyl)-1,3-dioxo-N-(3-pyridinylmethyl)-; Picolyl-substituted Isoindoledione Carboxamide
EINECS	Contact for details

Quality Control

Our 2-(2-Methylpropyl)-1,3-Dioxo-n-(Pyridin-3-Ylmethyl)-2,3-Dihydro-1H-Isoindole-5-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.