Description

2-Pyridinemethanol,α-2-Propynyl-,(Alphar)-(9Ci) is a specialized chiral pyridine derivative that serves as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for asymmetric synthesis and chiral ligand preparation.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Intermediate for the production of advanced, targeted pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: Valuable reagent for methodological development in organic synthesis and medicinal chemistry.
• Material Science Precursor: Potential starting material for functionalized polymers or metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Pyridinemethanol,α-2-Propynyl-,(Alphar)-(9Ci)
CAS No.	517907-63-0
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	(αR)-α-(2-Propynyl)-2-pyridinemethanol; (R)-α-Propargyl-2-pyridinemethanol; (R)-1-(Pyridin-2-yl)-3-butyn-2-ol; (R)-α-Propargyl-2-pyridylmethanol; (R)-2-(1-Hydroxy-3-butyn-2-yl)pyridine; (R)-Propargyl(2-pyridyl)methanol; (R)-α-Propargyl-2-picolyl alcohol; (R)-α-(2-Propynyl)-2-picolyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Pyridinemethanol,α-2-Propynyl-,(Alphar)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC, GC), to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.