Description

3-Pyridinemethanol,α-2-Propynyl-,(Alphar)-(9Ci) is a specialized chiral building block featuring a pyridine core substituted with a propargyl alcohol moiety. This compound matters for its role as a key intermediate in the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of new active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder research.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex specialty chemicals and advanced materials.
• Academic and Industrial R&D: A valuable tool for medicinal chemistry programs and methodological studies in organic synthesis.

Basic Information

Product Name	3-Pyridinemethanol,α-2-Propynyl-,(Alphar)-(9Ci)
CAS No.	517907-62-9
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	(αR)-α-(2-Propyn-1-yl)-3-pyridinemethanol; (R)-α-Propargyl-3-pyridinemethanol; (R)-1-(3-Pyridyl)-3-butyn-1-ol; (R)-3-(1-Hydroxy-3-butyn-1-yl)pyridine; α-Propargyl-3-pyridinemethanol (Alphar isomer); (R)-α-Propargyl-3-pyridylmethanol; (R)-3-(1-Hydroxybut-3-yn-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as chiral purity (enantiomeric excess), chemical purity (by HPLC), and residual solvent content are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.