Description

Methyl 5-(4-Fluorophenyl)Isoxazole-3-Carboxylate is a high-value fluorinated heterocyclic building block, specifically an isoxazole derivative, essential for advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for lead optimization and the creation of new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole and fluorophenyl moieties.
• Chemical Biology Probe: Used in medicinal chemistry to study protein-ligand interactions and for the discovery of new biological targets.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or organic electronic materials due to its rigid, conjugated structure.
• Custom Synthesis & Contract Manufacturing: An important building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Methyl 5-(4-Fluorophenyl)Isoxazole-3-Carboxylate
CAS No.	517870-16-5
Molecular Formula	C11H8FNO3
Molecular Weight	221.19 g/mol
Synonyms	Methyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate; 5-(4-Fluorophenyl)isoxazole-3-carboxylic acid methyl ester; 3-Carbomethoxy-5-(4-fluorophenyl)isoxazole; Methyl 5-(p-fluorophenyl)isoxazole-3-carboxylate; 517870-16-5; 5-(4-Fluorophenyl)-3-isoxazolecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-(4-Fluorophenyl)Isoxazole-3-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical R&D and can provide material compliant with ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.