Description

Butanedioic Acid, (3,6-Dihydro-1,1-Dioxido-2H-1,2-Thiazin-2-Yl)-, Dimethyl Ester, (2S) is a high-purity chiral sulfonamide derivative of succinic acid, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific stereochemistry and functional groups enable precise molecular construction. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutics, particularly in areas requiring sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological or metabolic disorders.
• Chiral Synthesis: Utilized in asymmetric synthesis to introduce specific stereocenters into complex organic molecules.
• Protease Inhibitor Research: Serves as a core scaffold or precursor in the development of enzyme inhibitors due to its sulfonamide moiety.
• Chemical Biology Probes: Used in the design and creation of molecular probes for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific API development projects.
• Academic Research: Employed in university and institutional laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Butanedioic Acid, (3,6-Dihydro-1,1-Dioxido-2H-1,2-Thiazin-2-Yl)-, Dimethyl Ester, (2S)
CAS No.	515130-18-4
Molecular Formula	C10H15NO6S
Molecular Weight	277.29 g/mol
Synonyms	(2S)-2-(3,6-Dihydro-1,1-dioxido-2H-1,2-thiazin-2-yl)butanedioic acid dimethyl ester; Dimethyl (2S)-2-(1,1-dioxido-3,6-dihydro-2H-1,2-thiazin-2-yl)succinate; (S)-Dimethyl 2-(1,1-dioxido-3,6-dihydro-2H-1,2-thiazin-2-yl)succinate; (2S)-2-(1,1-Dioxido-3,6-dihydro-2H-1,2-thiazin-2-yl)succinic Acid Dimethyl Ester; L-Sulfonamide Succinate Dimethyl Ester Derivative; 515130-18-4; Butanedioic acid, 2-(3,6-dihydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-, dimethyl ester, (2S)-
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Quality Control

Our Butanedioic Acid, (3,6-Dihydro-1,1-Dioxido-2H-1,2-Thiazin-2-Yl)-, Dimethyl Ester, (2S) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All materials are characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.