Description

2(3H)-Isothiazoleacetic Acid, α-Methyl-, Methyl Ester, 1,1-Dioxide, (Alphas) is a specialized, high-purity chemical building block of significant interest in advanced organic synthesis. Its unique sulfone and ester functionalized isothiazole core makes it a valuable intermediate for constructing complex molecules with targeted biological or material properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting neurological or anti-infective pathways.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for novel polymers or functional materials where the sulfone group can impart specific thermal or chemical resistance.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	2(3H)-Isothiazoleacetic Acid, α-Methyl-, Methyl Ester, 1,1-Dioxide, (Alphas)
CAS No.	515130-03-7
Molecular Formula	C7H9NO4S
Molecular Weight	203.21 g/mol
Synonyms	Methyl 2-methyl-1,1-dioxo-1,2-thiazolidine-3-acetate; 3-(Methoxycarbonylmethyl)-2-methylisothiazolidine 1,1-dioxide; α-Methyl-2(3H)-isothiazoleacetic acid methyl ester 1,1-dioxide; (Alphas)-Methyl 2-methyl-1,1-dioxo-1λ6,2-thiazolidine-3-acetate; 2-Methylisothiazolidine-3-acetic acid methyl ester S,S-dioxide; 515130-03-7; (Alphas) isomer of the methyl ester.
EINECS	Contact for details

Quality Control

Every batch of 2(3H)-Isothiazoleacetic Acid, α-Methyl-, Methyl Ester, 1,1-Dioxide, (Alphas) is manufactured under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles to ensure it meets the exacting standards required for research and synthesis. Our quality protocols are designed to support cGMP and ISO compliant workflows for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.