Description

2-[(5-Formyl-2-Methoxybenzyl)Thio]-4-Methyl-6-(Trifluoromethyl)Nicotinonitrile is a high-value, multifunctional chemical intermediate characterized by its unique trifluoromethyl and formyl-substituted heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific functional groups enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and inhibitors for enzyme and receptor studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	2-[(5-Formyl-2-Methoxybenzyl)Thio]-4-Methyl-6-(Trifluoromethyl)Nicotinonitrile
CAS No.	514856-37-2
Molecular Formula	C₁₇H₁₃F₃N₂O₂S
Molecular Weight	366.36 g/mol
Synonyms	2-[(5-Formyl-2-methoxybenzyl)sulfanyl]-4-methyl-6-(trifluoromethyl)pyridine-3-carbonitrile; 2-((5-Formyl-2-methoxybenzyl)thio)-4-methyl-6-(trifluoromethyl)nicotinonitrile; 514856-37-2; Nicotinonitrile, 2-[(5-formyl-2-methoxybenzyl)thio]-4-methyl-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-[(5-formyl-2-methoxybenzyl)thio]-4-methyl-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2-[(5-Formyl-2-Methoxybenzyl)Thio]-4-Methyl-6-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.