Description

2-[(5-Formyl-2-Methoxybenzyl)Thio]-4-Phenyl-6-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its complex molecular architecture, featuring a nicotinonitrile core with formyl, methoxy, phenyl, and trifluoromethyl substituents, makes it a critical intermediate for developing novel active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the nicotinonitrile and trifluoromethyl groups.
• Material Science: Acts as a building block for creating specialized organic ligands, dyes, or functional polymers with unique electronic or optical properties.
• Chemical Biology Probe Development: The reactive formyl and thioether groups make it suitable for constructing molecular probes to study enzyme function or protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-[(5-Formyl-2-Methoxybenzyl)Thio]-4-Phenyl-6-(Trifluoromethyl)Nicotinonitrile
CAS No.	514843-28-8
Molecular Formula	C22H15F3N2O2S
Molecular Weight	428.43 g/mol
Synonyms	4-Phenyl-2-[[(5-formyl-2-methoxyphenyl)methyl]thio]-6-(trifluoromethyl)-3-pyridinecarbonitrile; 2-((5-Formyl-2-methoxybenzyl)thio)-4-phenyl-6-(trifluoromethyl)nicotinonitrile; Nicotinonitrile, 2-[(5-formyl-2-methoxybenzyl)thio]-4-phenyl-6-(trifluoromethyl)-; CAS 514843-28-8
EINECS	Contact for details

Quality Control

Every batch of 2-[(5-Formyl-2-Methoxybenzyl)Thio]-4-Phenyl-6-(Trifluoromethyl)Nicotinonitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.