Description

Methyl 6-Bromo-3-Chloro-5-Fluoropicolinate CAS NO 514798-19-7 is a high-purity, multi-halogenated picolinate ester building block of significant importance in advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on novel active ingredients, where precise functionalization is critical. Its reliable quality and consistent supply are paramount for accelerating R&D timelines and ensuring reproducible manufacturing processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized picolinate-derived ligands for metal-organic frameworks (MOFs) and catalytic systems.
• Material Science Research: Employed in the creation of functionalized organic molecules for electronic materials and specialty polymers.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
• Academic and Industrial R&D: Facilitates exploratory chemistry in university and corporate laboratories focused on medicinal chemistry and chemical biology.

Basic Information

Product Name	Methyl 6-Bromo-3-Chloro-5-Fluoropicolinate
CAS No.	514798-19-7
Molecular Formula	C7H4BrClFNO2
Molecular Weight	268.47 g/mol
Synonyms	Methyl 6-bromo-3-chloro-5-fluoropyridine-2-carboxylate; 6-Bromo-3-chloro-5-fluoropicolinic acid methyl ester; 2-Pyridinecarboxylic acid, 6-bromo-3-chloro-5-fluoro-, methyl ester; Methyl 6-bromo-3-chloro-5-fluoropyridine-2-carboxylate; 6-Bromo-3-chloro-5-fluoro-2-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Bromo-3-Chloro-5-Fluoropicolinate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.