Description

3-Chloro-5-Fluoro-4-Pyridinecarboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated pyridine structure makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for designing molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	3-Chloro-5-Fluoro-4-Pyridinecarboxylic Acid
CAS No.	514798-03-9
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.55 g/mol
Synonyms	3-Chloro-5-fluoropyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-chloro-5-fluoro-; 3-Chloro-5-fluoro-4-carboxypyridine; 3-Chloro-5-fluoropyridine-4-carboxylic acid; 3-Chloro-5-fluoro-4-pyridinecarboxylic acid; 3-Chloro-5-fluoro-4-picolinic acid; 3-Chloro-5-fluoroisonicotinic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-4-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.