Description

2-Bromo-5-Chloro-3-Fluoropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Material Science: Used in the research and production of advanced electronic materials, liquid crystals, and organic light-emitting diodes (OLEDs).
• Chemical Research: A valuable reagent in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution for introducing complexity into molecular architectures.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Bromo-5-Chloro-3-Fluoropyridine
CAS No.	514797-97-8
Molecular Formula	C5H2BrClFN
Molecular Weight	210.43 g/mol
Synonyms	2-Bromo-5-chloro-3-fluoropyridine; 3-Fluoro-2-bromo-5-chloropyridine; 5-Chloro-2-bromo-3-fluoropyridine; Pyridine, 2-bromo-5-chloro-3-fluoro-; 2-Bromo-5-chloro-3-fluoro-pyridine; 514797-97-8; BCPF
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-3-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.