Description

2H-Pyrrol-2-One, 4-Acetyl-1-(4-Chlorophenyl)-5-(1,4-Dioxaspiro[4.5]Dec-8-Yl)-1,5-Dihydro-3-Hydroxy- is a sophisticated heterocyclic building block featuring a pyrrolone core integrated with a spirocyclic ketal moiety. This compound is of significant interest for its potential as a key intermediate in advanced organic synthesis, particularly in the development of novel pharmacologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing spirocyclic scaffolds.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its complex structure for unique biological activity.
• Chemical Biology Probe: Acts as a specialized building block for creating molecular probes to study enzyme function or protein interactions.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers with specific thermal or optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in synthetic organic chemistry and heterocycle formation.

Basic Information

Product Name	2H-Pyrrol-2-One, 4-Acetyl-1-(4-Chlorophenyl)-5-(1,4-Dioxaspiro[4.5]Dec-8-Yl)-1,5-Dihydro-3-Hydroxy-
CAS No.	512177-95-6
Molecular Formula	C22H26ClNO5
Molecular Weight	419.90 g/mol
Synonyms	4-Acetyl-1-(4-chlorophenyl)-5-(1,4-dioxaspiro[4.5]dec-8-yl)-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one; 1-(4-Chlorophenyl)-4-acetyl-5-(1,4-dioxaspiro[4.5]dec-8-yl)-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one; 512177-95-6; 4-Acetyl-1-(4-chlorophenyl)-5-(1,4-dioxaspiro[4.5]decan-8-yl)-3-hydroxypyrrol-2(5H)-one; Spirocyclic Pyrrolone Derivative
EINECS	Contact for details

Quality Control

Our 2H-Pyrrol-2-One, 4-Acetyl-1-(4-Chlorophenyl)-5-(1,4-Dioxaspiro[4.5]Dec-8-Yl)-1,5-Dihydro-3-Hydroxy- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or moisture-sensitive; prolonged exposure to light, heat, or humidity should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.