Description

4-tert-Butoxycarbonylaminobut-2-Enoic Acid Ethyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in the development of novel pharmaceuticals and bioactive molecules, offering a versatile handle for peptide coupling and molecular diversification. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex organic targets.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetics & Peptide Chemistry: Used to introduce protected amino acid functionalities into peptide chains and peptidomimetic structures.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Chemical Biology Probes: Acts as a precursor for labeled or modified amino acids used in biochemical and cellular studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for bespoke chemical manufacturing.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis.

Basic Information

Product Name	4-tert-Butoxycarbonylaminobut-2-Enoic Acid Ethyl Ester
CAS No.	510729-27-8
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	Ethyl (E)-4-((tert-Butoxycarbonyl)amino)but-2-enoate; Boc-NH-CH=CH-CH2-COOEt; (E)-Ethyl 4-((tert-butoxycarbonyl)amino)but-2-enoate; 4-(Boc-amino)crotonic Acid Ethyl Ester; N-Boc-dehydroaminobutyric Acid Ethyl Ester; tert-Butyl (1-ethoxy-1-oxobut-2-en-4-yl)carbamate; Dehydroaminobutyric Acid Derivative
EINECS	Contact for details

Quality Control

Our 4-tert-Butoxycarbonylaminobut-2-Enoic Acid Ethyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.