Description

4-Isobutoxy-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where a functionalized piperidine scaffold is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific piperidine-based structures for activity.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances that utilize complex amine chemistry.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) and isobutoxy groups offer orthogonal protection/deprotection pathways in multi-step synthesis.

Basic Information

Product Name	4-Isobutoxy-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	509147-80-2
Molecular Formula	C15H29NO3
Molecular Weight	271.40 g/mol
Synonyms	tert-Butyl 4-(isobutoxy)piperidine-1-carboxylate; 1-Boc-4-isobutoxypiperidine; 1-(tert-Butoxycarbonyl)-4-isobutoxypiperidine; 4-(2-Methylpropoxy)piperidine-1-carboxylic acid tert-butyl ester; Piperidine-1-carboxylic acid, 4-(2-methylpropoxy)-, 1,1-dimethylethyl ester; 509147-80-2; Boc-4-isobutoxypiperidine
EINECS	Contact for details

Quality Control

Our 4-Isobutoxy-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.