Description

tert-Butyl 4-(Methoxymethyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Peptidomimetic Chemistry: Used to introduce constrained, substituted piperidine motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: Employed in the creation of novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized to build molecular tools for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific, protected amine functionality.

Basic Information

Product Name	tert-Butyl 4-(Methoxymethyl)Piperidine-1-Carboxylate
CAS No.	509147-78-8
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	1-Boc-4-(Methoxymethyl)piperidine; 4-(Methoxymethyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(methoxymethyl)-1-piperidinecarboxylate; N-Boc-4-(Methoxymethyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(methoxymethyl)piperidine; BOC-4-Methoxymethylpiperidine; 509147-78-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Methoxymethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP development and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.