Description

cis-4-(2-Aminoethyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester CAS NO 509143-12-8 is a specialized organic compound featuring a cyclohexyl ring with an aminoethyl substituent in the cis configuration, protected by a tert-butyl ester group. This molecular architecture makes it a valuable high-purity intermediate for synthesizing complex molecules where precise stereochemistry and functional group protection are critical. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Peptide Mimetics & Conjugates: Used to introduce the cis-4-(2-aminoethyl)cyclohexyl moiety into peptide backbones to modulate stability and bioavailability.
• Ligand Synthesis for Catalysis: Serves as a precursor for chiral ligands used in asymmetric synthesis and homogeneous catalysis.
• Advanced Material Monomers: Incorporated into specialty polymers and dendrimers to impart specific structural and functional properties.
• Agrochemical Research: Intermediate in the development of new generation herbicides and plant growth regulators with tailored activity.
• Bioconjugation & Probe Development: Utilized in creating molecular probes and diagnostic agents for biochemical research.

Basic Information

Product Name	cis-4-(2-Aminoethyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester
CAS No.	509143-12-8
Molecular Formula	C14H27NO2
Molecular Weight	241.37 g/mol
Synonyms	tert-Butyl (cis-4-(2-aminoethyl)cyclohexyl)carbamate; N-Boc-cis-4-(2-Aminoethyl)cyclohexylamine; Boc-cis-4-(2-Aminoethyl)cyclohexylamine; (cis-4-(2-Aminoethyl)cyclohexyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl N-[cis-4-(2-aminoethyl)cyclohexyl]carbamate; N-(tert-Butoxycarbonyl)-cis-4-(2-aminoethyl)cyclohexylamine; BOC-CIS-4-(2-AMINOETHYL)CYCLOHEXYLAMINE
EINECS	Contact for details

Quality Control

Our cis-4-(2-Aminoethyl)Cyclohexyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with full traceability are available upon request, and we support compliance with cGMP and REACH requirements for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.