Description

Fmoc-(S)-3-Amino-3-(3-Pyridyl)-Propionic Acid is a high-purity, non-natural amino acid derivative featuring an Fmoc-protected amine group and a pyridyl side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the precise incorporation of a heterocyclic aromatic moiety into peptide sequences. It is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptides.
• Pharmaceutical Research: Used in the development of peptide drugs targeting GPCRs, enzymes, and other biological receptors where the pyridyl group can enhance binding affinity or solubility.
• Combinatorial Chemistry: Serves as a versatile scaffold for generating diverse peptide libraries for high-throughput screening.
• Bioconjugation: The carboxylic acid group allows for conjugation to other molecules, carriers, or surfaces to create targeted bioprobes.
• Chemical Biology: Employed in the synthesis of peptide mimetics and molecular probes to study protein-protein interactions and cellular signaling pathways.
• Agrochemical Research: Potential use in the design of bioactive peptides for crop protection.

Basic Information

Product Name	Fmoc-(S)-3-Amino-3-(3-Pyridyl)-Propionic Acid
CAS No.	507472-06-2
Molecular Formula	C23H20N2O4
Molecular Weight	388.42 g/mol
Synonyms	Fmoc-3-(3-Pyridyl)-D-alanine; Fmoc-3-(3-Pyridinyl)-D-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-pyridinyl)-D-alanine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(pyridin-3-yl)propanoic acid; Fmoc-D-3-(3-Pyridyl)alanine; Fmoc-D-3-Pyridylalanine; Fmoc-(R)-3-Amino-3-(3-pyridyl)propionic acid; N-Fmoc-3-(3-pyridyl)-D-alanine
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-3-Amino-3-(3-Pyridyl)-Propionic Acid is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, meeting the exacting standards required for peptide synthesis. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and identity confirmation. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring reliable batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.