Description

5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block of significant importance in modern organic synthesis. This compound, with CAS number 507462-51-3, is valued for its unique fused bicyclic structure, which serves as a critical scaffold in the development of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery programs, particularly for kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and tool compounds to study biological pathways.
• Material Science: Potential building block for organic electronic materials and functional polymers due to its electron-rich heterocyclic core.
• Academic & Contract Research: Essential for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Amine
CAS No.	507462-51-3
Molecular Formula	C7H6BrN3
Molecular Weight	212.05 g/mol
Synonyms	5-Bromo-3-amino-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-amine; 3-Amino-5-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-ylamine; 5-Bromo-3-aminopyrrolo[2,3-b]pyridine; 5-Bromo-7-azaindol-3-amine; 5-Bromo-3-amino-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.